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Possible tumor suppressor. Activates p53 in response to UV light, causing growth arrest and apoptosis. Required for cisplatin-induced apoptosis (Medline:14729469). Downregulated in breast and thyroid carcinomas. OMIM Gene Id: 606868.
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Retrieved from "http://semanticweb.org/wiki/Special:Browse/Possible-20tumor-20suppressor.-20Activates-20p53-20in-20response-20to-20UV-20light,-20causing-20growth-20arrest-20and-20apoptosis.-20Required-20for-20cisplatin-2Dinduced-20apoptosis-20(Medline:14729469).-20Downregulated-20in-20breast-20and-20thyroid-20carcinomas.-20OMIM-20Gene-20Id:-20606868."
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